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Expansion of HIV-specific T follicular helper cells in chronic HIV infection

HIV targets CD4 T cells, which are required for the induction of high-affinity antibody responses and the formation of long-lived B cell memory. The depletion of antigen-specific CD4 T cells during HIV infection is therefore believed to impede the development of protective B cell immunity. Although...

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Detalhes bibliográficos
Main Authors: Lindqvist, Madelene, van Lunzen, Jan, Soghoian, Damien Z., Kuhl, Bjorn D., Ranasinghe, Srinika, Kranias, Gregory, Flanders, Michael D., Cutler, Samuel, Yudanin, Naomi, Muller, Matthias I., Davis, Isaiah, Farber, Donna, Hartjen, Philip, Haag, Friedrich, Alter, Galit, Schulze zur Wiesch, Julian, Streeck, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428098/
https://ncbi.nlm.nih.gov/pubmed/22922259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64314
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