Expansion of HIV-specific T follicular helper cells in chronic HIV infection

HIV targets CD4 T cells, which are required for the induction of high-affinity antibody responses and the formation of long-lived B cell memory. The depletion of antigen-specific CD4 T cells during HIV infection is therefore believed to impede the development of protective B cell immunity. Although...

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Hlavní autoři: Lindqvist, Madelene, van Lunzen, Jan, Soghoian, Damien Z., Kuhl, Bjorn D., Ranasinghe, Srinika, Kranias, Gregory, Flanders, Michael D., Cutler, Samuel, Yudanin, Naomi, Muller, Matthias I., Davis, Isaiah, Farber, Donna, Hartjen, Philip, Haag, Friedrich, Alter, Galit, Schulze zur Wiesch, Julian, Streeck, Hendrik
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428098/
https://ncbi.nlm.nih.gov/pubmed/22922259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64314
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