Expansion of HIV-specific T follicular helper cells in chronic HIV infection

HIV targets CD4 T cells, which are required for the induction of high-affinity antibody responses and the formation of long-lived B cell memory. The depletion of antigen-specific CD4 T cells during HIV infection is therefore believed to impede the development of protective B cell immunity. Although...

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Autors principals: Lindqvist, Madelene, van Lunzen, Jan, Soghoian, Damien Z., Kuhl, Bjorn D., Ranasinghe, Srinika, Kranias, Gregory, Flanders, Michael D., Cutler, Samuel, Yudanin, Naomi, Muller, Matthias I., Davis, Isaiah, Farber, Donna, Hartjen, Philip, Haag, Friedrich, Alter, Galit, Schulze zur Wiesch, Julian, Streeck, Hendrik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428098/
https://ncbi.nlm.nih.gov/pubmed/22922259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64314
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