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PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells

A single nucleotide polymorphism in the protein tyrosine phosphatase nonreceptor type 22 gene (PTPN22), that encodes the Lyp tyrosine phosphatase LypR620W, has been linked to a number of autoimmune diseases including type I diabetes, rheumatoid arthritis and systemic lupus erythematosus. Studies in...

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Autors principals: Maine, Christian J., Marquardt, Kristi, Cheung, Jocelyn, Sherman, Linda A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933017/
https://ncbi.nlm.nih.gov/pubmed/24453256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302418
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