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The Effect of the Autoimmunity-Associated Gene, PTPN22, on the BXSB Model of Lupus
A single nucleotide polymorphism in PTPN22 is linked to increased disease susceptibility in a range of autoimmune diseases including systemic lupus erythematosus (SLE). PTPN22 encodes the Lyp phosphatase that dampens TCR signaling and is necessary for signaling downstream of toll-like receptors in m...
Kaydedildi:
| Yayımlandı: | Clin Immunol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291082/ https://ncbi.nlm.nih.gov/pubmed/25463433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.11.003 |
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