Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The mechanisms by which maternal nutrient restriction (MNR) causes reduced fetal growth are poorly understood. We hypothesized that MNR inhibits placental mechanistic target of rapamycin (mTOR) and insulin/IGF-I signaling, down-regulates placental nutrient transporters, and decreases fetal amino aci...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Kavitha, Jovita V., Rosario, Fredrick J., Nijland, Mark J., McDonald, Thomas J., Wu, Guoyao, Kanai, Yoshikatsu, Powell, Theresa L., Nathanielsz, Peter W., Jansson, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2014
Onderwerpen:
Research Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929672/
https://ncbi.nlm.nih.gov/pubmed/24334703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-242271
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items