Gene targeting in primary human trophoblasts

Por Rosario, Fredrick J, Sadovsky, Yoel, Jansson, Thomas
Publicado em 2012

Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth

Por Rosario, Fredrick J., Powell, Theresa L., Jansson, Thomas
Publicado no Am J Physiol Regul Integr Comp Physiol (2015)

Mechanistic target of rapamycin (mTOR) regulates trophoblast folate uptake by modulating the cell surface expression of FR-α and the RFC

Por Rosario, Fredrick J., Powell, Theresa L., Jansson, Thomas
Publicado no Sci Rep (2016)

mTOR folate sensing links folate availability to trophoblast cell function

Por Rosario, Fredrick J., Powell, Theresa L., Jansson, Thomas
Publicado no J Physiol (2017)

Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

Por Rosario, Fredrick J, Kanai, Yoshikatsu, Powell, Theresa L, Jansson, Thomas
Publicado em 2013

Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth

Por Rosario, Fredrick J, Kanai, Y, Powell, Theresa L, Jansson, Thomas
Publicado no Obesity (Silver Spring) (2015)

Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function

Por Silva, Elena, Rosario, Fredrick J, Powell, Theresa L, Jansson, Thomas
Publicado no J Nutr (2017)

Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

Por Rosario, Fredrick J., Nathanielsz, Peter W., Powell, Theresa L., Jansson, Thomas
Publicado no Sci Rep (2017)

Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy

Por Díaz, Paula, Harris, Jessica, Rosario, Fredrick J., Powell, Theresa L., Jansson, Thomas
Publicado no Am J Physiol Regul Integr Comp Physiol (2015)

Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

Por Aye, Irving L. M. H., Rosario, Fredrick J., Powell, Theresa L., Jansson, Thomas
Publicado no Proc Natl Acad Sci U S A (2015)

Reply to Carbillon: Fetal/placental weight ratio and placental function

Por Aye, Irving L. M. H., Rosario, Fredrick J., Powell, Theresa L., Jansson, Thomas
Publicado no Proc Natl Acad Sci U S A (2016)

Regulation of Amino Acid Transporter Trafficking by mTORC1 in Primary Human Trophoblast cells is Mediated by the Ubiquitin Ligase Nedd4-2

Por Rosario, Fredrick J, Dimasuay, Kris Genelyn, Kanai, Y, Powell, Theresa L, Jansson, Thomas
Publicado no Clin Sci (Lond) (2015)

Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth

Por Rosario, Fredrick J, Schumacher, Michael A, Jiang, Jean, Kanai, Yoshikatsu, Powell, Theresa L, Jansson, Thomas
Publicado em 2012

Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

Por Rosario, Fredrick J., Jansson, Nina, Kanai, Yoshikatsu, Prasad, Puttur D., Powell, Theresa L., Jansson, Thomas
Publicado em 2011

Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

Por Chen, Yi-Yung, Rosario, Fredrick J., Shehab, Majida Abu, Powell, Theresa L., Gupta, Madhulika B., Jansson, Thomas
Publicado no Clin Sci (Lond) (2015)

Down-Regulation of Placental Transport of Amino Acids Precedes the Development of Intrauterine Growth Restriction in Maternal Nutrient Restricted Baboons

Por Pantham, Priyadarshini, Rosario, Fredrick J., Weintraub, Susan T., Nathanielsz, Peter W., Powell, Theresa L., Li, Cun, Jansson, Thomas
Publicado no Biol Reprod (2016)

Activation of Placental mTOR Signaling and Amino Acid Transporters in Obese Women Giving Birth to Large Babies

Por Jansson, Nina, Rosario, Fredrick J., Gaccioli, Francesca, Lager, Susanne, Jones, Helen N., Roos, Sara, Jansson, Thomas, Powell, Theresa L.
Publicado em 2013

Liver mTOR Controls IGF-I Bioavailability by Regulation of Protein Kinase CK2 and IGFBP-1 Phosphorylation in Fetal Growth Restriction

Por Abu Shehab, Majida, Damerill, Ian, Shen, Tong, Rosario, Fredrick J., Nijland, Mark, Nathanielsz, Peter W., Kamat, Amrita, Jansson, Thomas, Gupta, Madhulika B.
Publicado em 2014

Reduced placental amino acid transport in response to maternal nutrient restriction in the baboon

Por Pantham, Priyadarshini, Rosario, Fredrick J., Nijland, Mark, Cheung, Alex, Nathanielsz, Peter W., Powell, Theresa L., Galan, Henry L., Li, Cun, Jansson, Thomas
Publicado no Am J Physiol Regul Integr Comp Physiol (2015)

Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

Por Kavitha, Jovita V., Rosario, Fredrick J., Nijland, Mark J., McDonald, Thomas J., Wu, Guoyao, Kanai, Yoshikatsu, Powell, Theresa L., Nathanielsz, Peter W., Jansson, Thomas
Publicado em 2014