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Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

Abnormal fetal growth increases the risk for perinatal complications and predisposes for the development of obesity, diabetes and cardiovascular disease later in life. Emerging evidence suggests that changes in placental amino acid transport directly contribute to altered fetal growth. However, the...

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Main Authors: Rosario, Fredrick J, Kanai, Yoshikatsu, Powell, Theresa L, Jansson, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577540/
https://ncbi.nlm.nih.gov/pubmed/23165769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.238014
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