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mTOR folate sensing links folate availability to trophoblast cell function
KEY POINTS: Folate deficiency during pregnancy is associated with restricted fetal growth, although the underlying mechanisms are poorly understood. Here we show that mechanistic target of rapamycin (mTOR) functions as a folate sensor in primary human trophoblast (PHT) cells. Folate sensing by mTOR...
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| Published in: | J Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491891/ https://ncbi.nlm.nih.gov/pubmed/28374905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272424 |
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