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Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

Maternal folate deficiency is linked to restricted fetal growth, however the underlying mechanisms remain to be established. Here we tested the hypothesis that mTOR functions as a folate sensor in vivo in mice and that maternal folate deficiency inhibits placental mTOR signaling and amino acid trans...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Rosario, Fredrick J., Nathanielsz, Peter W., Powell, Theresa L., Jansson, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479823/
https://ncbi.nlm.nih.gov/pubmed/28638048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03888-2
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