Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

The mechanisms underlying reduced fetal growth in response to maternal protein restriction are not well established. Maternal levels of insulin, IGF-I, and leptin are decreased in rats fed a low protein (LP) diet. Because these hormones stimulate placental amino acid transporters in vitro, we hypoth...

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Hlavní autoři: Rosario, Fredrick J., Jansson, Nina, Kanai, Yoshikatsu, Prasad, Puttur D., Powell, Theresa L., Jansson, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Reproduction-Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858644/
https://ncbi.nlm.nih.gov/pubmed/21285325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1153
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