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Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters
The mechanisms underlying reduced fetal growth in response to maternal protein restriction are not well established. Maternal levels of insulin, IGF-I, and leptin are decreased in rats fed a low protein (LP) diet. Because these hormones stimulate placental amino acid transporters in vitro, we hypoth...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Endocrine Society
2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858644/ https://ncbi.nlm.nih.gov/pubmed/21285325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1153 |
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