Cargando...

Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation

The transcriptional repressors BCL6 and BACH2 are crucial regulators of germinal center (GC) B-cell fate, and are known to interact and repress transcription of PRDM1, a key driver of plasma cell differentiation. How these factors cooperate is not fully understood. Herein, we show that GC formation...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Huang, Chuanxin, Geng, Huimin, Boss, Isaac, Wang, Ling, Melnick, Ari
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924924/
https://ncbi.nlm.nih.gov/pubmed/24277074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-518605
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!