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Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation
The transcriptional repressors BCL6 and BACH2 are crucial regulators of germinal center (GC) B-cell fate, and are known to interact and repress transcription of PRDM1, a key driver of plasma cell differentiation. How these factors cooperate is not fully understood. Herein, we show that GC formation...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924924/ https://ncbi.nlm.nih.gov/pubmed/24277074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-518605 |
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