Intermittent Metronomic Drug Schedule Is Essential for Activating Antitumor Innate Immunity and Tumor Xenograft Regression

Antzeko izenburuak

• Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2
  nork: Doloff, Joshua C, et al.
  Argitaratua: (2014)
• Transcriptional profiling provides insights into metronomic cyclophosphamide-activated, innate immune-dependent regression of brain tumor xenografts
  nork: Doloff, Joshua C, et al.
  Argitaratua: (2015)
• VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression
  nork: Doloff, Joshua C., et al.
  Argitaratua: (2012)
• Metronomic cyclophosphamide schedule-dependence of innate immune cell recruitment and tumor regression in an implanted glioma model
  nork: Wu, Junjie, et al.
  Argitaratua: (2014)
• Metronomic cyclophosphamide activation of anti-tumor immunity: tumor model, mouse host, and drug schedule dependence of gene responses and their upstream regulators
  nork: Wu, Junjie, et al.
  Argitaratua: (2016)