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Intermittent Metronomic Drug Schedule Is Essential for Activating Antitumor Innate Immunity and Tumor Xenograft Regression

Metronomic chemotherapy using cyclophosphamide (CPA) is widely associated with antiangiogenesis; however, recent studies implicate other immune-based mechanisms, including antitumor innate immunity, which can induce major tumor regression in implanted brain tumor models. This study demonstrates the...

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Hlavní autoři: Chen, Chong-Sheng, Doloff, Joshua C, Waxman, David J
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924543/
https://ncbi.nlm.nih.gov/pubmed/24563621
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