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Transcriptional profiling provides insights into metronomic cyclophosphamide-activated, innate immune-dependent regression of brain tumor xenografts

BACKGROUND: Cyclophosphamide treatment on a six-day repeating metronomic schedule induces a dramatic, innate immune cell-dependent regression of implanted gliomas. However, little is known about the underlying mechanisms whereby metronomic cyclophosphamide induces innate immune cell mobilization and...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Doloff, Joshua C, Waxman, David J
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523019/
https://ncbi.nlm.nih.gov/pubmed/25952672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1358-y
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