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Intermittent Metronomic Drug Schedule Is Essential for Activating Antitumor Innate Immunity and Tumor Xenograft Regression

Metronomic chemotherapy using cyclophosphamide (CPA) is widely associated with antiangiogenesis; however, recent studies implicate other immune-based mechanisms, including antitumor innate immunity, which can induce major tumor regression in implanted brain tumor models. This study demonstrates the...

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Bibliografiske detaljer
Main Authors: Chen, Chong-Sheng, Doloff, Joshua C, Waxman, David J
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924543/
https://ncbi.nlm.nih.gov/pubmed/24563621
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