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VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression

In metronomic chemotherapy, frequent drug administration at lower than maximally tolerated doses can improve activity while reducing the dose-limiting toxicity of conventional dosing schedules. Although the anti-tumor activity produced by metronomic chemotherapy is attributed widely to anti-angiogen...

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Detalles Bibliográficos
Main Authors: Doloff, Joshua C., Waxman, David J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294103/
https://ncbi.nlm.nih.gov/pubmed/22237627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3380
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