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Metronomic cyclophosphamide schedule-dependence of innate immune cell recruitment and tumor regression in an implanted glioma model

Metronomic cyclophosphamide (CPA) treatment activates robust innate anti-tumor immunity and induces major regression of large, implanted brain tumor xenografts when administered on an intermittent, every 6-day schedule, but not on a daily low-dose or a maximum-tolerated dose CPA schedule. Here, we u...

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Bibliographic Details
Main Authors: Wu, Junjie, Waxman, David J.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162810/
https://ncbi.nlm.nih.gov/pubmed/25069038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.07.033
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