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SIRT4 Protein Suppresses Tumor Formation in Genetic Models of Myc-induced B Cell Lymphoma

Glutamine metabolism plays an essential role for growth and proliferation of many cancer cells by providing metabolites for the maintenance of mitochondrial functions and macromolecular synthesis. Aberrant activation of the transcription factor c-Myc, e.g. caused by t(8;14) chromosomal translocation...

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Detalles Bibliográficos
Main Authors: Jeong, Seung Min, Lee, Annie, Lee, Jaewon, Haigis, Marcia C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924279/
https://ncbi.nlm.nih.gov/pubmed/24368766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525949
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