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SIRT4 Protein Suppresses Tumor Formation in Genetic Models of Myc-induced B Cell Lymphoma

Glutamine metabolism plays an essential role for growth and proliferation of many cancer cells by providing metabolites for the maintenance of mitochondrial functions and macromolecular synthesis. Aberrant activation of the transcription factor c-Myc, e.g. caused by t(8;14) chromosomal translocation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jeong, Seung Min, Lee, Annie, Lee, Jaewon, Haigis, Marcia C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924279/
https://ncbi.nlm.nih.gov/pubmed/24368766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525949
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