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SirT1 Is an Inhibitor of Proliferation and Tumor Formation in Colon Cancer
The NAD-dependent deacetylase SirT1 regulates factors involved in stress response and cell survival and is a potential drug target of activators and inhibitors. Determination of SirT1 function in tumor cells is important for its targeting in cancer therapy. We found that SirT1 knockdown by short hai...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709385/ https://ncbi.nlm.nih.gov/pubmed/19433578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000034 |
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