The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition of lens epithelial cells

Proliferation and epithelial–mesenchymal transition (EMT) of lens epithelium cells (LECs) may contribute to anterior subcapsular cataract (ASC) and posterior capsule opacification (PCO), which are important causes of visual impairment. Histone deacetylases (HDACs)-mediated epigenetic mechanism has a...

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Bibliografiset tiedot
Päätekijät: Chen, X, Xiao, W, Chen, W, Luo, L, Ye, S, Liu, Y
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2013
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920942/
https://ncbi.nlm.nih.gov/pubmed/24157878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.416
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