Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition in retinal pigment epithelium cells

The proliferation and epithelial–mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cells are the major pathological changes in development of proliferative vitreoretinopathy (PVR), which leads to severe visual impairment. Histone deacetylases (HDACs)-mediated epigenetic mechanisms pla...

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Bibliografski detalji
Glavni autori: Xiao, Wei, Chen, Xiaoyun, Liu, Xialin, Luo, Lixia, Ye, Shaobi, Liu, Yizhi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons Ltd 2014
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000116/
https://ncbi.nlm.nih.gov/pubmed/24456602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12212
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