Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition in retinal pigment epithelium cells

The proliferation and epithelial–mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cells are the major pathological changes in development of proliferative vitreoretinopathy (PVR), which leads to severe visual impairment. Histone deacetylases (HDACs)-mediated epigenetic mechanisms pla...

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Autors principals: Xiao, Wei, Chen, Xiaoyun, Liu, Xialin, Luo, Lixia, Ye, Shaobi, Liu, Yizhi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons Ltd 2014
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000116/
https://ncbi.nlm.nih.gov/pubmed/24456602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12212
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