Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition in retinal pigment epithelium cells

The proliferation and epithelial–mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cells are the major pathological changes in development of proliferative vitreoretinopathy (PVR), which leads to severe visual impairment. Histone deacetylases (HDACs)-mediated epigenetic mechanisms pla...

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Main Authors: Xiao, Wei, Chen, Xiaoyun, Liu, Xialin, Luo, Lixia, Ye, Shaobi, Liu, Yizhi
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons Ltd 2014
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000116/
https://ncbi.nlm.nih.gov/pubmed/24456602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12212
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