Epigenetic reprogramming of epithelial mesenchymal transition in triple negative breast cancer cells with DNA methyltransferase and histone deacetylase inhibitors

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive neoplasia with no effective therapy. Our laboratory has developed a unique TNBC cell model presenting epithelial mesenchymal transition (EMT) a process known to be important for tumor progression and metastasis. There is increasing ev...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Su, Yanrong, Hopfinger, Nathan R., Nguyen, Theresa D., Pogash, Thomas J., Santucci-Pereira, Julia, Russo, Jose
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295063/
https://ncbi.nlm.nih.gov/pubmed/30547810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0988-8
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