Histone Methyltransferase SETD1A Induces Epithelial-Mesenchymal Transition to Promote Invasion and Metastasis Through Epigenetic Reprogramming of Snail in Gastric Cancer

Aberrant epigenetic modification induces oncogene expression and promotes cancer development. The histone lysine methyltransferase SETD1A, which specifically methylates histone 3 lysine 4 (H3K4), is involved in tumor growth and metastasis, and its ectopic expression has been detected in aggressive m...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Cell Dev Biol
Main Authors: Wu, Jugang, Chai, Hongjuan, Shan, Haiyan, Pan, Chunpeng, Xu, Xin, Dong, Wenpei, Yu, Jiwei, Gu, Yan
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021
נושאים:
Cell and Developmental Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215546/
https://ncbi.nlm.nih.gov/pubmed/34164392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.657888
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