Histone Methyltransferase SETD1A Induces Epithelial-Mesenchymal Transition to Promote Invasion and Metastasis Through Epigenetic Reprogramming of Snail in Gastric Cancer

Aberrant epigenetic modification induces oncogene expression and promotes cancer development. The histone lysine methyltransferase SETD1A, which specifically methylates histone 3 lysine 4 (H3K4), is involved in tumor growth and metastasis, and its ectopic expression has been detected in aggressive m...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Wu, Jugang, Chai, Hongjuan, Shan, Haiyan, Pan, Chunpeng, Xu, Xin, Dong, Wenpei, Yu, Jiwei, Gu, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215546/
https://ncbi.nlm.nih.gov/pubmed/34164392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.657888
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