Histone Methyltransferase SETD1A Induces Epithelial-Mesenchymal Transition to Promote Invasion and Metastasis Through Epigenetic Reprogramming of Snail in Gastric Cancer

Aberrant epigenetic modification induces oncogene expression and promotes cancer development. The histone lysine methyltransferase SETD1A, which specifically methylates histone 3 lysine 4 (H3K4), is involved in tumor growth and metastasis, and its ectopic expression has been detected in aggressive m...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Wu, Jugang, Chai, Hongjuan, Shan, Haiyan, Pan, Chunpeng, Xu, Xin, Dong, Wenpei, Yu, Jiwei, Gu, Yan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215546/
https://ncbi.nlm.nih.gov/pubmed/34164392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.657888
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