Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates

Flap endonuclease 1 (Fen1) is a highly conserved structure-specific nuclease that catalyses a specific incision to remove 5′ flaps in double-stranded DNA substrates. Fen1 plays an essential role in key cellular processes, such as DNA replication and repair, and mutations that compromise Fen1 express...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Craggs, Timothy D., Hutton, Richard D., Brenlla, Alfonso, White, Malcolm F., Penedo, J. Carlos
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Nucleic Acid Enzymes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919604/
https://ncbi.nlm.nih.gov/pubmed/24234453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1116
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker