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PCNA and XPF cooperate to distort DNA substrates

XPF is a structure-specific endonuclease that preferentially cleaves 3′ DNA flaps during a variety of repair processes. The crystal structure of a crenarchaeal XPF protein bound to a DNA duplex yielded insights into how XPF might recognise branched DNA structures, and recent kinetic data have demons...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hutton, Richard D., Craggs, Timothy D., White, Malcolm F., Penedo, J.Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836553/
https://ncbi.nlm.nih.gov/pubmed/20008103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1104
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