The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase

There is compelling evidence that proliferating cell nuclear antigen (PCNA), a DNA sliding clamp, co-ordinates the processing and joining of Okazaki fragments during eukaryotic DNA replication. However, a detailed mechanistic understanding of functional PCNA:ligase I interactions has been incomplete...

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Autori principali: Vijayakumar, Sangeetha, Chapados, Brian R., Schmidt, Kristina H., Kolodner, Richard D., Tainer, John A., Tomkinson, Alan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2007
Soggetti:
Nucleic Acid Enzymes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865074/
https://ncbi.nlm.nih.gov/pubmed/17308348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm006
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