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Point mutations in the Rpb9-homologous domain of Rpc11 that impair transcription termination by RNA polymerase III
RNA polymerase III recognizes and pauses at its terminator, an oligo(dT) tract in non-template DNA, terminates 3′ oligo(rU) synthesis within this sequence, and releases the RNA. The pol III subunit Rpc11p (C11) mediates RNA 3′–5′ cleavage in the catalytic center of pol III during pausing. The amino...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152337/ https://ncbi.nlm.nih.gov/pubmed/21450810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr182 |
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