Nalaganje...
Genetic Instability Induced by Overexpression of DNA Ligase I in Budding Yeast
Recombination and microsatellite mutation in humans contribute to disorders including cancer and trinucleotide repeat (TNR) disease. TNR expansions in wild-type yeast may arise by flap ligation during lagging-strand replication. Here we show that overexpression of DNA ligase I (CDC9) increases the r...
Shranjeno v:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Copyright © 2005 by the Genetics Society of America
2005
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456761/ https://ncbi.nlm.nih.gov/pubmed/15965249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.042861 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|