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DNA ligase I, the replicative DNA ligase
Multiple DNA ligation events are required to join the Okazaki fragments generated during lagging strand DNA synthesis. In eukaryotes, this is primarily carried out by members of the DNA ligase I family. The C-terminal catalytic region of these enzymes is composed of three domains: a DNA binding doma...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881551/ https://ncbi.nlm.nih.gov/pubmed/22918593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-007-4572-8_17 |
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