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DNA ligase I, the replicative DNA ligase

Multiple DNA ligation events are required to join the Okazaki fragments generated during lagging strand DNA synthesis. In eukaryotes, this is primarily carried out by members of the DNA ligase I family. The C-terminal catalytic region of these enzymes is composed of three domains: a DNA binding doma...

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Detalhes bibliográficos
Main Authors: Howes, Timothy R.L., Tomkinson, Alan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881551/
https://ncbi.nlm.nih.gov/pubmed/22918593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-007-4572-8_17
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