Phosphorylation of Human DNA Ligase I Regulates Its Interaction with Replication Factor C and Its Participation in DNA Replication and DNA Repair

Human DNA ligase I (hLigI) participates in DNA replication and excision repair via an interaction with proliferating cell nuclear antigen (PCNA), a DNA sliding clamp. In addition, hLigI interacts with and is inhibited by replication factor C (RFC), the clamp loader complex that loads PCNA onto DNA....

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Main Authors: Vijayakumar, Sangeetha, Dziegielewska, Barbara, Levin, David S., Song, Wei, Yin, Jinhu, Yang, Austin, Matsumoto, Yoshihiro, Bermudez, Vladimir P., Hurwitz, Jerard, Tomkinson, Alan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663303/
https://ncbi.nlm.nih.gov/pubmed/19223468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01732-08
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