Phosphorylation of Serine 51 Regulates the Interaction of Human DNA Ligase I with Replication Factor C and Its Participation in DNA Replication and Repair

Human DNA ligase I (hLigI) joins Okazaki fragments during DNA replication and completes excision repair via interactions with proliferating cell nuclear antigen and replication factor C (RFC). Unlike proliferating cell nuclear antigen, the interaction with RFC is regulated by hLigI phosphorylation....

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Detalhes bibliográficos
Main Authors: Peng, Zhimin, Liao, Zhongping, Dziegielewska, Barbara, Matsumoto, Yoshi, Thomas, Stefani, Wan, Yunhu, Yang, Austin, Tomkinson, Alan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481275/
https://ncbi.nlm.nih.gov/pubmed/22952233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383570
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