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Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex

The synthesis, processing, and joining of Okazaki fragments during DNA replication is complex, requiring the sequential action of a large number of proteins. Proliferating cell nuclear antigen, a DNA sliding clamp, interacts with and coordinates the activity of several DNA replication proteins, incl...

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Publicado en:J Biol Chem
Autores principales: Peng, Zhimin, Liao, Zhongping, Matsumoto, Yoshihiro, Yang, Austin, Tomkinson, Alan E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063974/
https://ncbi.nlm.nih.gov/pubmed/27573245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.746198
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