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Artemis interacts with the Cul4A-DDB1(DDB2) ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27
Artemis, a member of the SNM1 gene family, is a multifunctional phospho-protein that has been shown to have important roles in V(D)J recombination, DNA double-strand break repair and stress-induced cell cycle checkpoint regulation. We show here that Artemis interacts with the Cul4A-DDB1 E3 ubiquitin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272290/ https://ncbi.nlm.nih.gov/pubmed/22134138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.23.18227 |
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