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E3 Ligase RFWD3 Participates in Replication Checkpoint Control

RFWD3 has E3 ligase activity in vitro, but its in vivo function remains unknown. In this study we identified RFWD3 as a novel replication protein A (RPA)-associated protein. Using purified proteins, we observed a direct interaction between RPA2 and RFWD3. Further analysis showed that RFWD3 is recrui...

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Detalhes bibliográficos
Main Authors: Gong, Zihua, Chen, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121377/
https://ncbi.nlm.nih.gov/pubmed/21504906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.222869
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