RING Finger and WD Repeat Domain 3 (RFWD3) Associates with Replication Protein A (RPA) and Facilitates RPA-mediated DNA Damage Response

DNA damage response is crucial for maintaining genomic integrity and preventing cancer by coordinating the activation of checkpoints and the repair of damaged DNA. Central to DNA damage response are the two checkpoint kinases ATM and ATR that phosphorylate a wide range of substrates. RING finger and...

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Detalhes bibliográficos
Main Authors: Liu, Shangfeng, Chu, Jessica, Yucer, Nur, Leng, Mei, Wang, Shih-Ya, Chen, Benjamin P. C., Hittelman, Walter N., Wang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121378/
https://ncbi.nlm.nih.gov/pubmed/21558276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.222802
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