RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks

We have used quantitative proteomics to profile ubiquitination in the DNA damage response (DDR). We demonstrate that RPA, which functions as a protein scaffold in the replication stress response, is multiply ubiquitinated upon replication fork stalling. Ubiquitination of RPA occurs on chromatin, inv...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Elia, Andrew E.H., Wang, David C., Willis, Nicholas A., Boardman, Alexander P., Hajdu, Ildiko, Adeyemi, Richard O., Lowry, Elizabeth, Gygi, Steven P., Scully, Ralph, Elledge, Stephen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609029/
https://ncbi.nlm.nih.gov/pubmed/26474068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.09.011
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