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A protective role for BRCA2 at stalled replication forks
The hereditary breast and ovarian cancer predisposition genes BRCA1 and BRCA2 account for the lion's share of heritable breast cancer risk in the human population. Loss of function of either gene results in defective homologous recombination (HR) and triggers genomic instability, accelerating b...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262192/ https://ncbi.nlm.nih.gov/pubmed/21996371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2918 |
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