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BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks
Replication fork stalling can promote genomic instability, predisposing to cancer and other diseases(1–3). Stalled replication forks may be processed by sister chromatid recombination (SCR), generating error-free or error-prone homologous recombination (HR) outcomes(4–8). In mammalian cells, a long-...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118467/ https://ncbi.nlm.nih.gov/pubmed/24776801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13295 |
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