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BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control
Human TopBP1 plays a critical role in the control of DNA replication checkpoint. In this study, we report a specific interaction between TopBP1 and BACH1/FANCJ, a DNA helicase involved in the repair of DNA cross-links. The TopBP1/BACH1 interaction is mediated by the very C-terminal tandem BRCT domai...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695484/ https://ncbi.nlm.nih.gov/pubmed/20159562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.01.002 |
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