Llwytho...

BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control

Human TopBP1 plays a critical role in the control of DNA replication checkpoint. In this study, we report a specific interaction between TopBP1 and BACH1/FANCJ, a DNA helicase involved in the repair of DNA cross-links. The TopBP1/BACH1 interaction is mediated by the very C-terminal tandem BRCT domai...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gong, Zihua, Kim, Ja-Eun, Leung, Charles Chung Yun, Glover, J N Mark, Chen, Junjie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695484/
https://ncbi.nlm.nih.gov/pubmed/20159562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.01.002
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