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Evolutionary instability of CUG-Leu in the genetic code of budding yeasts

The genetic code used in nuclear genes is almost universal, but here we report that it changed three times in parallel during the evolution of budding yeasts. All three changes were reassignments of the codon CUG, which is translated as serine (in 2 yeast clades), alanine (1 clade), or the ‘universa...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Krassowski, Tadeusz, Coughlan, Aisling Y., Shen, Xing-Xing, Zhou, Xiaofan, Kominek, Jacek, Opulente, Dana A., Riley, Robert, Grigoriev, Igor V., Maheshwari, Nikunj, Shields, Denis C., Kurtzman, Cletus P., Hittinger, Chris Todd, Rokas, Antonis, Wolfe, Kenneth H.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951914/
https://ncbi.nlm.nih.gov/pubmed/29760453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04374-7
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