Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase

DNA-binding proteins utilise different recognition mechanisms to locate their DNA targets; some proteins recognise specific DNA sequences, while others interact with specific DNA structures. While sequence-specific DNA binding has been studied extensively, structure-specific recognition mechanisms r...

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Udgivet i:Nucleic Acids Res
Main Authors: Craggs, Timothy D, Sustarsic, Marko, Plochowietz, Anne, Mosayebi, Majid, Kaju, Hendrik, Cuthbert, Andrew, Hohlbein, Johannes, Domicevica, Laura, Biggin, Philip C, Doye, Jonathan P K, Kapanidis, Achillefs N
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Nucleic Acid Enzymes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846080/
https://ncbi.nlm.nih.gov/pubmed/31544938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz797
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