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Conformational transitions in DNA polymerase I revealed by single-molecule FRET
The remarkable fidelity of most DNA polymerases depends on a series of early steps in the reaction pathway which allow the selection of the correct nucleotide substrate, while excluding all incorrect ones, before the enzyme is committed to the chemical step of nucleotide incorporation. The conformat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818957/ https://ncbi.nlm.nih.gov/pubmed/20080740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910909107 |
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