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Break-induced replication: functions and molecular mechanism

Break-induced replication (BIR) is the pathway of homologous recombination (HR) conserved from phages to eukaryotes that serves to repair DNA breaks that have only one end. BIR contributes to the repair of broken replication forks and allows telomere lengthening in the absence of telomerase. Nonalle...

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Detalhes bibliográficos
Main Authors: Malkova, Anna, Ira, Grzegorz
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915057/
https://ncbi.nlm.nih.gov/pubmed/23790415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2013.05.007
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