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Break Induced Replication in eukaryotes: mechanisms, functions, and consequences

Break-Induced Replication (BIR) is an important pathway specializing in repair of one-ended double-strand DNA breaks (DSBs). This type of DSB break typically arises at collapsed replication forks or at eroded telomeres. BIR initiates by invasion of a broken DNA end into a homologous template followe...

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Bibliographic Details
Published in:Crit Rev Biochem Mol Biol
Main Authors: Sakofsky, Cynthia J., Malkova, Anna
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763318/
https://ncbi.nlm.nih.gov/pubmed/28427283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2017.1314444
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